Symposium 20：Programmatic Management of DSTB: Progress and Challenges
Standard regimen with 2HERZ/4HER was very effective for drug susceptible tuberculosis. However, it was still too long for TB patient and also had many side effects like hepatitis which will interrupt TB treatment. To find short course regimen less than 4 months for DSTB with good effectiveness and less toxicity is crucial for the elimination of TB. Repurposed drug like rifapentine , linezolid , clofazimine , high dose rifampicin , new generation fluoroquinolnes and new developed drug like bedaquiline , pretomanid and demlamanid make the dream come true. How to design short course regimen from animal study to clinical implementation is very interesting topics and helpful for the TB clinicians.